The role of peripheral opiate antagonists in pain medicine and perioperative care.
نویسندگان
چکیده
BACKGROUND AND OBJECTIVES Pre-clinical and clinical trials of peripheral opiate antagonists have shed new light on the effects of exogenous and endogenous opioids. CONTENTS This article review preclinical studies and clinical opioid bowel disfunction trials. CONCLUSIONS If approved these drugs may offer potential solutions to important clinical problems in pain management.
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ورودعنوان ژورنال:
- Revista brasileira de anestesiologia
دوره 58 5 شماره
صفحات -
تاریخ انتشار 2008